Description

Almotriptan Metabolite M2 is a key intermediate and reference standard in the development and quality control of the migraine medication Almotriptan. This compound is critical for pharmaceutical research and manufacturing, enabling precise metabolic profiling and ensuring drug purity and efficacy. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and analytical laboratories involved in drug development, pharmacokinetic studies, and regulatory compliance testing.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification and quantification of Almotriptan metabolites in bioanalytical studies.
• Metabolite Research: Essential for conducting in-vitro and in-vivo metabolism studies to understand the drug's pharmacokinetic profile.
• Impurity Profiling: Employed in the development and validation of analytical methods (e.g., HPLC, LC-MS) to monitor and control related substances in active pharmaceutical ingredient (API) batches.
• Drug Development & Synthesis: Serves as a crucial intermediate or marker in the synthetic pathway and process optimization for Almotriptan production.
• Regulatory Submissions: Provides necessary data and materials for regulatory filings (e.g., FDA, EMA) to demonstrate comprehensive understanding of the drug's metabolic fate.
• Quality Control (QC) Testing: Integral to the QC laboratories for routine testing of Almotriptan API to ensure it meets stringent pharmacopeial specifications.

Basic Information

Product Name	Almotriptan Metabolite M2
CAS No.	603137-41-3
Molecular Formula	C₁₇H₂₅N₃O₃S
Molecular Weight	351.47 g/mol
Synonyms	N-Desmethyl Almotriptan; Almotriptan N-Desmethyl Metabolite; 3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indole N-Desmethyl Derivative; 1H-Indole-3-ethanamine, N,α-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-, N-Desmethyl-; Almotriptan Impurity; Almotriptan Related Compound M2
EINECS	Contact for details

Quality Control

Our Almotriptan Metabolite M2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for pharmaceutical analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.