Description

2-Fluoro-4-(Methoxycarbonyl)Benzeneboronic Acid is a versatile and high-purity boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
• Material Science: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-4-(Methoxycarbonyl)Benzeneboronic Acid
CAS No.	603122-84-5
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	(2-Fluoro-4-(methoxycarbonyl)phenyl)boronic acid; 4-Carbomethoxy-2-fluorophenylboronic acid; 2-Fluoro-4-methoxycarbonylbenzeneboronic acid; Methyl 2-fluoro-4-boronobenzoate; 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid; Benzeneboronic acid, 2-fluoro-4-(methoxycarbonyl)-; 603122-84-5
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Methoxycarbonyl)Benzeneboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (by HPLC/NMR), purity, and impurity profiles. Our quality commitment supports applications in cGMP and non-GMP environments alike.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.