Description

2-Fluoro-4-(Methoxycarbonyl)Phenylboronic Acid,Pinacol Ester is a high-purity, protected boronic acid ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its stability and reactivity, serving as a key intermediate in the synthesis of complex molecules through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs producing client-specific fine chemicals.

Basic Information

Product Name	2-Fluoro-4-(Methoxycarbonyl)Phenylboronic Acid,Pinacol Ester
CAS No.	603122-79-8
Molecular Formula	C14H18BFO4
Molecular Weight	280.10 g/mol
Synonyms	(4-(Methoxycarbonyl)-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-4-(methoxycarbonyl)benzeneboronic acid pinacol ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluorobenzoate; 3-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester; Pinacol [2-fluoro-4-(methoxycarbonyl)phenyl]boronate; Boronic acid, B-[4-(methoxycarbonyl)-2-fluorophenyl]-, 1,1-dimethylethyl ester (9CI); 603122-79-8
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Methoxycarbonyl)Phenylboronic Acid,Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.