Description

Pyrrolidine, 2-(3-Fluoro-5-Methylphenyl)-4-Methyl- (9Ci) is a high-purity, fluorinated pyrrolidine derivative, identified by CAS number 603068-84-4, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a substituted pyrrolidine ring with a fluorinated aromatic system, enabling precise structural modifications in complex molecule synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research, where the fluorine atom and pyrrolidine moiety are crucial for bioactivity and metabolic stability.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging its structural features to enhance target binding and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, facilitating the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with tailored optical or electronic properties.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and biological pathways due to its ability to mimic natural substrates.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions for clinical trial material production.

Basic Information

Product Name	Pyrrolidine, 2-(3-Fluoro-5-Methylphenyl)-4-Methyl- (9Ci)
CAS No.	603068-84-4
Molecular Formula	C12H16FN
Molecular Weight	193.26 g/mol
Synonyms	2-(3-Fluoro-5-methylphenyl)-4-methylpyrrolidine; 4-Methyl-2-(3-fluoro-5-methylphenyl)pyrrolidine; 2-(3-Fluoro-5-methylphenyl)-4-methyl-1-azacyclopentane; 1-Azacyclopentane, 2-(3-fluoro-5-methylphenyl)-4-methyl-; (3-Fluoro-5-methylphenyl)-4-methylpyrrolidine; Pyrrolidine, 2-(3-fluoro-5-methylphenyl)-4-methyl-
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 2-(3-Fluoro-5-Methylphenyl)-4-Methyl- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to research-grade and custom synthesis specifications to meet the precise requirements of your development project.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Research Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.