Description

2-Chloro-4-(Trifluoromethyl)Phenylacetic Acid is a high-purity, versatile arylacetic acid derivative distinguished by its trifluoromethyl and chloro substituents. This compound is a critical building block in advanced organic synthesis, offering unique electronic and steric properties that are essential for developing novel active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often confers improved activity and selectivity.
• Liquid Crystal & OLED Materials: Used in the synthesis of specialty chemicals for electronic applications, including liquid crystal displays and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed as a standard or building block in academic and industrial R&D labs for method development and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects, supporting the production of complex, high-value specialty chemicals on a contract basis.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Phenylacetic Acid
CAS No.	601513-26-2
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	[2-Chloro-4-(trifluoromethyl)phenyl]acetic acid; 2-Chloro-α-(trifluoromethyl)phenylacetic Acid; (2-Chloro-4-trifluoromethylphenyl)acetic Acid; 2-Chloro-4-(trifluoromethyl)benzeneacetic Acid; α-(2-Chloro-4-(trifluoromethyl)phenyl)acetic Acid; 601513-26-2; 2-Chloro-4-trifluoromethylphenylacetic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.