Description

Acetamide,n-(5-Acetyl-6-Ethyl-2,3-Dihydro-1H-Inden-2-Yl)-2,2,2-Trifluoro- is a specialized trifluoroacetamide derivative featuring a unique indane core structure, making it a high-value synthetic intermediate. Its molecular architecture is engineered to introduce specific steric and electronic properties into target molecules, which is critical for advanced material and pharmaceutical research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the indane and trifluoromethyl groups can contribute to biological activity and environmental persistence profiles.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, or organic electronic materials that benefit from its rigid, fused-ring structure.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for developing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Acetamide,n-(5-Acetyl-6-Ethyl-2,3-Dihydro-1H-Inden-2-Yl)-2,2,2-Trifluoro-
CAS No.	601487-89-2
Molecular Formula	C₁₅H₁₆F₃NO₂
Molecular Weight	299.29 g/mol
Synonyms	N-(5-Acetyl-6-ethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(5-acetyl-6-ethyl-2,3-dihydro-1H-inden-2-yl)acetamide; 5-Acetyl-6-ethyl-2,3-dihydro-1H-inden-2-amine trifluoroacetamide derivative; 601487-89-2; TFAI Derivative (Indane-based); Trifluoroacetamide indane intermediate
EINECS	Contact for details

Quality Control

Every batch of Acetamide,n-(5-Acetyl-6-Ethyl-2,3-Dihydro-1H-Inden-2-Yl)-2,2,2-Trifluoro- is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.