Description

D-Threo-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its protected amino and hydroxyl functionalities, which make it a versatile intermediate for constructing complex molecules with precise stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), nucleoside analogs, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly nucleoside-based drugs and antiviral compounds.
• Organic Synthesis Building Block: Used in multi-step syntheses to introduce specific stereocenters and functional groups into complex molecular architectures.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme-substrate interaction research.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide analogs and mimetics due to its sugar-like backbone and protected amine.
• Asymmetric Catalysis: Can be utilized as a ligand precursor or chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Academic & Industrial R&D: Essential for exploratory chemistry in universities and corporate R&D labs focusing on medicinal chemistry and chemical biology.

Basic Information

Item	Detail
Product Name	D-Threo-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	600728-78-7
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	3-Deoxy-3-[(tert-butoxycarbonyl)amino]-D-threo-pentitol; 3-[(tert-Butoxycarbonyl)amino]-3-deoxy-D-threo-pentitol; 3-Amino-3-deoxy-D-threo-pentitol, N-Boc derivative; Boc-D-3-Amino-3-deoxypentitol; tert-Butyl N-(1,2,4-trihydroxybutyl)carbamate (D-threo-); D-Threo-1,2,4-butanetriol, 1-amino-, N-Boc derivative; (2R,3S)-2,3,4-Trihydroxybutylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of D-Threo-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- (9Ci) is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.