Description

(R)-2-Amino-n-tert-Butyl-3-Methylbutanamide is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional groups, which make it a critical building block for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereocontrol is essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for APIs requiring specific (R)-configured amino acid derivatives.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Peptidomimetics Research: Serves as a constrained, tert-butyl-containing backbone unit in the design of peptide analogs and mimetics for drug discovery.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	(R)-2-Amino-n-tert-Butyl-3-Methylbutanamide
CAS No.	69981-34-6
Molecular Formula	C9H20N2O
Molecular Weight	172.27 g/mol
Synonyms	(R)-2-Amino-3,3-dimethyl-N-(1,1-dimethylethyl)butanamide; (R)-2-Amino-N-tert-butyl-3,3-dimethylbutyramide; (R)-H-Dmt-NH-tBu; (R)-2-Amino-N-(tert-butyl)-3,3-dimethylbutanamide; tert-Butyl (R)-2-amino-3,3-dimethylbutyrate amide; (R)-α-Amino-β,β-dimethyl-N-tert-butylbutyramide
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-n-tert-Butyl-3-Methylbutanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.