Description

Dopamine 3-β-D-Glucuronide Sodium Salt is a high-purity conjugated metabolite of the essential neurotransmitter dopamine. This compound is critical for research and development in neurochemistry and pharmacology, serving as a key reference standard and analytical tool. It is primarily utilized by pharmaceutical R&D laboratories, clinical diagnostic manufacturers, and academic institutions focused on metabolic pathway analysis and biomarker discovery.

Application

• Pharmaceutical Reference Standard: Used for the quantification and qualification of dopamine metabolites in drug metabolism and pharmacokinetic (DMPK) studies.
• Clinical Diagnostics: Serves as a calibrator and control in the development of LC-MS/MS assays for measuring neurotransmitter metabolites in biological fluids.
• Neurochemical Research: Essential for investigating the glucuronidation pathway of dopamine, a key mechanism in neurotransmitter regulation and clearance.
• Biomarker Analysis: Employed in studies exploring the correlation between dopamine metabolite levels and neurological conditions or drug responses.
• Enzyme Activity Assays: Acts as a substrate or standard in assays for UDP-glucuronosyltransferase (UGT) enzyme activity.
• Quality Control: Used in the quality assurance processes for the production of related diagnostic kits and pharmaceutical ingredients.

Basic Information

Product Name	Dopamine 3-β-D-Glucuronide Sodium Salt
CAS No.	69975-91-3
Molecular Formula	C15H19NO8•Na
Molecular Weight	364.30 g/mol
Synonyms	Dopamine 3-O-β-D-Glucuronide Sodium Salt; 4-(2-Aminoethyl)-1,2-benzenediol 3-(β-D-Glucopyranosiduronic Acid) Sodium Salt; Dopamine 3-Glucuronide Sodium; 3-O-(β-D-Glucopyranosyluronic acid)dopamine sodium salt; DA-3-G Sodium Salt
EINECS	Contact for details

Quality Control

Our Dopamine 3-β-D-Glucuronide Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.