Description

Z-Trp-Obzl is a protected amino acid derivative, specifically the benzyl ester of Z-protected tryptophan. This compound is a crucial building block in peptide synthesis, offering a stable and reactive intermediate for constructing complex peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of tryptophan residues into peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the synthesis of specific peptide fragments.
• Pharmaceutical Research: Serves as a precursor in the development and manufacturing of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Can be used to attach peptide motifs to other molecules, proteins, or surfaces for drug delivery or diagnostic applications.
• Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, or fluorescent probes for biological studies.
• Academic Research: A standard reagent in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Z-Trp-Obzl
CAS No.	69876-37-5
Molecular Formula	C26H24N2O4
Molecular Weight	428.48 g/mol
Synonyms	N-Carbobenzyloxy-L-tryptophan benzyl ester; Z-L-Tryptophan benzyl ester; Nα-Cbz-L-tryptophan benzyl ester; Benzyl N-[(benzyloxy)carbonyl]-L-tryptophanate; CBZ-L-Tryptophan-OBzl; N-Cbz-L-Tryptophan-OBzl; (S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our Z-Trp-Obzl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing specific results for assay, optical rotation, and related substances is provided with every shipment to ensure consistency and traceability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-10.0° to -14.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.