Description

2-(2-Chlorophenyl)-2-Methylpropanenitrile is a specialized organic nitrile building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals where its unique chlorinated phenyl and tertiary nitrile structure offers valuable reactivity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and insecticides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers with enhanced properties.
• Chemical Research & Development: A versatile building block for exploring new carbon-carbon and carbon-nitrogen bond-forming reactions in academic and industrial labs.

Basic Information

Product Name	2-(2-Chlorophenyl)-2-Methylpropanenitrile
CAS No.	69849-08-7
Molecular Formula	C10H10ClN
Molecular Weight	179.64 g/mol
Synonyms	2-(2-Chlorophenyl)-2-methylpropionitrile; α-(2-Chlorophenyl)isobutyronitrile; 2-Methyl-2-(2-chlorophenyl)propanenitrile; 2-Chloro-α,α-dimethylbenzeneacetonitrile; (2-Chlorophenyl)(cyano)dimethylmethane; Isobutyronitrile, 2-(2-chlorophenyl)-; NSC 403119
EINECS	Contact for details

Quality Control

Our 2-(2-Chlorophenyl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.