Description

(2S,2'S)-4,4'-Dithiobis[2-(Trifluoroacetyl)Aminobutyric Acid Butyl] Ester is a high-purity, chiral organic compound featuring a disulfide bridge and trifluoroacetyl-protected amine groups, making it a valuable building block for advanced synthesis. This compound is specifically engineered for applications requiring precise stereochemistry and functional group compatibility, offering researchers and manufacturers a reliable intermediate with consistent performance. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and specialized materials where its unique structure enables the creation of complex, sulfur-containing target molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing disulfide linkages or requiring trifluoroacetyl protection strategies.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its sulfur-based core can contribute to specific biological activity and environmental stability.
• Peptide Chemistry & Mimetics: Serves as a crucial component for constructing peptide analogs and mimetics, enabling the introduction of disulfide bonds that are critical for protein folding and stability.
• Material Science: Employed in the synthesis of specialized polymers and functional materials that require incorporated sulfur or fluorine atoms for specific chemical or physical properties.
• Cross-linking Agent: Acts as a bifunctional cross-linker in biochemical and bioconjugation applications due to its reactive disulfide moiety.
• Chemical Synthesis Reagent: Provides a protected amine precursor for multi-step organic synthesis, facilitating complex molecular construction in research and development.

Basic Information

Product Name	(2S,2'S)-4,4'-Dithiobis[2-(Trifluoroacetyl)Aminobutyric Acid Butyl] Ester
CAS No.	69779-40-4
Molecular Formula	C22H30F6N2O6S2
Molecular Weight	596.61 g/mol
Synonyms	Butyl (2S)-2-[[(2S)-2-[[(2,2,2-Trifluoroacetyl)amino]-4-(butoxy)-4-oxobutyl]disulfanyl]-4-(butoxy)-4-oxobutyl]carbamate (2,2,2-Trifluoroacetate); L-Cystine, S,S'-bis(N-trifluoroacetyl-O-butyl-); Bis(butyl N-trifluoroacetyl-L-homocysteinate) disulfide; (2S,2'S)-4,4'-Disulfanediyldibutane-1,4-diyl bis(2,2,2-trifluoroacetate); Nα,Nα'-Bis(trifluoroacetyl)-L-cystine dibutyl ester; L-Cystine derivative (TFA, butyl ester).
EINECS	Contact for details

Quality Control

Our (2S,2'S)-4,4'-Dithiobis[2-(Trifluoroacetyl)Aminobutyric Acid Butyl] Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and optical rotation are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider sealing under an inert gas such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.