Description

Cefodizime is a third-generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. This semi-synthetic compound is valued for its enhanced stability against β-lactamases and its pharmacokinetic profile, making it a critical intermediate in pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical industry for the production of injectable antibiotic formulations targeting serious infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key active component in finished antibiotic drug products.
• Injectable Formulations: Manufacture of sterile injectable solutions and powders for injection, particularly for hospital-use antibiotics.
• Research & Development: Serves as a reference standard and key intermediate in antimicrobial R&D programs.
• Veterinary Medicine: Used in the development of antibacterial treatments for veterinary applications.
• Combinatorial Chemistry: Acts as a building block for creating novel cephalosporin derivatives and exploring new antibiotic classes.

Basic Information

Product Name	Cefodizime
CAS No.	69739-16-8
Molecular Formula	C20H20N6O7S4
Molecular Weight	584.66 g/mol
Synonyms	(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(5-carboxy-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefodizime Sodium; Cefodizime Free Acid; HR-221; THR-221; Antibiotic HR 221; (6R-trans)-
EINECS	Contact for details

Quality Control

Our Cefodizime is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identity, potency, and impurity profile verification. Certificates of Analysis (COA) compliant with current industry practices are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.10 EU/mg (for injectable grade)
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.