Description

(2S)-1-[4-(Dimethylamino)Butyryl]-2α-(3-Pyridinyl)Pyrrolidine is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it provides a critical, structurally defined building block for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and receptor-targeted therapies. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to ensure the stereochemical integrity and efficacy of their final drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs where the specific stereochemistry is crucial for biological activity.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-1-[4-(Dimethylamino)Butyryl]-2α-(3-Pyridinyl)Pyrrolidine
CAS No.	69730-92-3
Molecular Formula	C15H23N3O
Molecular Weight	261.36 g/mol
Synonyms	(2S)-1-[4-(Dimethylamino)butanoyl]-2-(pyridin-3-yl)pyrrolidine; 2-Pyridin-3-yl-1-(4-dimethylaminobutyryl)pyrrolidine, (2S)-; (S)-1-(4-(Dimethylamino)butyryl)-2-(pyridin-3-yl)pyrrolidine; (S)-2-(3-Pyridyl)-1-(4-dimethylaminobutyryl)pyrrolidine; (S)-N-[4-(Dimethylamino)butyryl]-2-(3-pyridyl)pyrrolidine; 1-(4-Dimethylaminobutyryl)-2-(3-pyridyl)-(S)-pyrrolidine; (2S)-2-(3-Pyridinyl)-1-[4-(dimethylamino)-1-oxobutyl]pyrrolidine
EINECS	Contact for details

Quality Control

Our (2S)-1-[4-(Dimethylamino)Butyryl]-2α-(3-Pyridinyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.