Description

Cefsulodin CAS NO 69705-63-1 is a semi-synthetic, third-generation cephalosporin antibiotic with potent activity against Pseudomonas aeruginosa. Its primary value lies in its targeted spectrum, making it a critical reference standard and active pharmaceutical ingredient (API) for research and development. This compound is essential for pharmaceutical manufacturers, clinical research laboratories, and microbiological quality control units requiring a reliable agent for susceptibility testing and anti-infective formulation.

Application

• Pharmaceutical API: Used as an active ingredient in the formulation of injectable antibiotics targeting Gram-negative infections, particularly those caused by P. aeruginosa.
• Microbiological Research: Serves as a critical tool for studying bacterial resistance mechanisms, pharmacokinetics, and the efficacy of combination therapies against resistant pathogens.
• Quality Control & Reference Standard: Employed as a certified reference material (CRM) in HPLC and microbiological assays to ensure the potency and purity of commercial antibiotic products.
• Clinical Diagnostics: Used in agar dilution and disk diffusion tests to determine the antibiotic susceptibility profiles of clinical bacterial isolates in hospital laboratories.
• Veterinary Medicine: Applied in the development of treatments for bacterial infections in animals, especially where Pseudomonas species are implicated.

Basic Information

Product Name	Cefsulodin
CAS No.	69705-63-1
Molecular Formula	C22H20N4O8S2
Molecular Weight	532.55 g/mol
Synonyms	Cefsulodin Sodium; Cefsulodine; SCE-129; Abbott-48999; (6R,7R)-7-[(R)-2-(4-Carbamoyl-2-thienyl)acetamido]-3-[(1-carboxy-1-pyridin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 3-[(1-Carboxy-1-pyridinio)methyl]-7-[(R)-2-(4-carbamoyl-2-thienyl)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Pseudomonic acid; Takecin
EINECS	274-085-5

Quality Control

Our Cefsulodin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent limits for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) that detail all test results, ensuring compliance with pharmacopeial standards for reference materials and API intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13 criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.