Description

19-D3-Testosterone is a deuterated analog of the primary male sex hormone, testosterone, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is of significant value for research and analytical applications where metabolic tracing and quantification are required. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and analytical service providers specializing in mass spectrometry and pharmacokinetic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS/MS and GC-MS analysis of endogenous testosterone levels in biological matrices.
• Pharmacokinetic and Metabolic Studies: Used as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of testosterone in preclinical and clinical research.
• Doping Control Analysis: Employed in sports anti-doping laboratories for the accurate identification and quantification of testosterone and its metabolites.
• Endocrine Disorder Research: Facilitates precise measurement of testosterone in studies related to hypogonadism, hormonal cancers, and other endocrine conditions.
• Method Development and Validation: Essential for developing and validating highly specific and sensitive bioanalytical assays in compliance with regulatory guidelines (e.g., FDA, EMA).
• Stable Isotope Labeling: Acts as a starting material or intermediate for the synthesis of more complex deuterated molecules for research purposes.

Basic Information

Product Name	19-D3-Testosterone
CAS No.	69660-28-2
Molecular Formula	C19H25D3O2
Molecular Weight	292.45 g/mol
Synonyms	19,19,19-Trideuterotestosterone; [19,19,19-2H3]-Testosterone; Testosterone-d3; 17β-Hydroxyandrost-4-en-3-one-19,19,19-d3; Androst-4-en-3-one, 17β-hydroxy-19,19,19-d3-, (17β)-; Deuterated Testosterone (19,19,19-d3)
EINECS	Contact for details

Quality Control

Our 19-D3-Testosterone is manufactured under controlled conditions to ensure high chemical and isotopic purity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (by HPLC), isotopic enrichment, and identification (by NMR and MS). We adhere to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.