Description

Boc-(S)-2-Amino-2-(4-Hydroxyphenyl)Acetic Acid is a protected amino acid derivative of significant importance in synthetic organic and medicinal chemistry. This compound serves as a crucial chiral building block for the synthesis of complex peptides and peptidomimetics, offering a versatile handle for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including enzyme inhibitors and bioactive peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a tyrosine-like residue with a protected amine (Boc) and a free phenolic hydroxyl group.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of inhibitors for various proteases.
• Chemical Biology Research: Employed in the synthesis of labeled peptides, affinity probes, and other tools for studying protein-protein interactions and enzyme mechanisms.
• Ligand Synthesis: Useful for creating chelating agents or modified amino acids for metal coordination studies.

Basic Information

Product Name	Boc-(S)-2-Amino-2-(4-Hydroxyphenyl)Acetic Acid
CAS No.	69651-48-5
Molecular Formula	C₁₃H₁₇NO₅
Molecular Weight	267.28 g/mol
Synonyms	N-Boc-L-tyrosine; (S)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid; Boc-Tyr-OH; Boc-L-Tyrosine; N-tert-Butoxycarbonyl-L-tyrosine; tert-Butyloxycarbonyl-L-tyrosine; BOC-L-Tyrosine; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-2-(4-hydroxyphenyl)acetic acid
EINECS	Contact for details

Quality Control

Our Boc-(S)-2-Amino-2-(4-Hydroxyphenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.