Description

Tirofiban-D6 is a deuterated analog of the antiplatelet drug Tirofiban, specifically labeled with six deuterium atoms. This compound is a critical non-radioactive internal standard used in quantitative bioanalytical methods, ensuring the highest accuracy and reliability in pharmacokinetic and metabolic studies. It is essential for pharmaceutical R&D laboratories, clinical research organizations, and analytical service providers engaged in the development and quality control of cardiovascular therapeutics.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the precise quantification of Tirofiban in biological matrices.
• Supporting pharmacokinetic (PK) and bioequivalence studies for generic and novel Tirofiban formulations.
• Enabling accurate metabolite profiling and drug metabolism studies in preclinical and clinical research.
• Quality control and method validation in pharmaceutical manufacturing to ensure batch consistency and purity.
• Use in forensic and anti-doping analysis for the definitive identification of Tirofiban.
• Application in academic research investigating platelet aggregation inhibitors and their mechanisms of action.

Basic Information

Product Name	Tirofiban-D6
CAS No.	69603-65-2
Molecular Formula	C22H30D6N2O5S
Molecular Weight	442.62 g/mol
Synonyms	N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine-d6; Tirofiban (d6); L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, (S)-, d6-; MK-383-d6; Aggrastat-d6; Tirofiban Internal Standard-d6; Deuterated Tirofiban
EINECS	Contact for details

Quality Control

Our Tirofiban-D6 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, purity (by HPLC), isotopic purity (by MS), and residual solvents. We adhere to relevant ISO guidelines and can provide material suitable for use in regulated environments under GLP/GMP.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98.0 atom % D
Chemical Purity (HPLC)	≥95.0%
Residual Solvents (GC)	Complies with ICH limits
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.