Description

Boc-Thr-Nhnh2 CAS NO 69568-63-4 is a protected amino acid derivative, specifically N-Boc-O-tert-butyl-L-threonine hydrazide, serving as a crucial building block in synthetic organic chemistry. This compound is essential for the controlled synthesis of peptides and other complex molecules, offering a reactive hydrazide group for conjugation and a Boc-protected amine for selective deprotection. It is primarily required by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel active compounds and advanced materials.

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the development and production of active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: The hydrazide functional group enables specific coupling reactions for labeling proteins, antibodies, or other biomolecules.
• Combinatorial Chemistry: Serves as a versatile building block in libraries for high-throughput screening and drug discovery.
• Agrochemical Development: Employed in the synthesis of novel pesticides and herbicides with specific biological activity.
• Material Science: Used to create functionalized polymers and advanced materials with tailored properties.

Basic Information

Product Name	Boc-Thr-Nhnh2
CAS No.	69568-63-4
Molecular Formula	C₁₃H₂₇N₃O₅
Molecular Weight	305.37 g/mol
Synonyms	N-Boc-O-tert-butyl-L-threonine hydrazide; (2S,3R)-2-[(tert-Butoxycarbonyl)amino]-3-[(2-methylpropan-2-yl)oxy]butanehydrazide; Boc-Thr(tBu)-NHNH₂; tert-Butyl N-[(1S,2R)-1-(hydrazinecarbonyl)-2-[(2-methylpropan-2-yl)oxy]propyl]carbamate; L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester, hydrazide; Boc-L-Thr(tBu)-NHNH₂
EINECS	Contact for details

Quality Control

Our Boc-Thr-Nhnh2 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure compliance with your research and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.