Description

9-Oxa-3-Azabicyclo[4.2.1]Non-7-Ene, 3-(Trifluoroacetyl)- (9Ci) is a sophisticated nitrogen-oxygen heterocyclic building block featuring a trifluoroacetyl-protected amine. This compound matters as a critical intermediate for advanced organic synthesis, offering a rigid bicyclic scaffold that is valuable for constructing complex molecular architectures. Pharmaceutical and agrochemical R&D teams need it for developing novel active ingredients, particularly where the introduction of fluorine atoms is desired to modulate biological activity, lipophilicity, and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in creating advanced pesticide and herbicide molecules where the bicyclic structure contributes to target specificity.
• Fluorine Chemistry Research: Serves as a versatile precursor for introducing the trifluoroacetyl group, a valuable motif in medicinal and materials chemistry.
• Ligand and Catalyst Development: The nitrogen atom within the constrained ring system can be utilized to create novel chelating ligands for catalytic applications.
• Advanced Material Precursor: Potential use in synthesizing specialty polymers or organic electronic materials with unique properties.

Basic Information

Product Name	9-Oxa-3-Azabicyclo[4.2.1]Non-7-Ene, 3-(Trifluoroacetyl)- (9Ci)
CAS No.	69496-61-3
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	3-(Trifluoroacetyl)-9-oxa-3-azabicyclo[4.2.1]non-7-ene; 9-Oxa-3-azabicyclo[4.2.1]non-7-ene, 3-(trifluoroacetyl)-; N-(Trifluoroacetyl)-9-oxa-3-azabicyclo[4.2.1]non-7-ene; Bicyclo[4.2.1]non-7-ene-3-carboxamide, N-(trifluoroacetyl)-9-oxa-; 69496-61-3; 3-Azabicyclo[4.2.1]non-7-ene-3-carboxylic acid, 9-oxa-, trifluoroacetyl derivative
EINECS	Contact for details

Quality Control

Our 9-Oxa-3-Azabicyclo[4.2.1]Non-7-Ene, 3-(Trifluoroacetyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept away from strong acids and organic solvents. Keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.