Description

Boc-4-Amino-3-Hydroxybutanoic Acid is a protected amino acid derivative of significant value in synthetic organic and medicinal chemistry. This compound serves as a crucial chiral building block for the construction of complex molecules, particularly in peptide mimetics and pharmaceutical intermediates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, reliable intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptide Mimetic Synthesis: Used to incorporate modified amino acid residues into peptide chains to enhance stability, bioavailability, or biological activity.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of enzyme inhibitors.
• Bioconjugation and Linker Chemistry: Utilized in the preparation of chemical linkers for antibody-drug conjugates (ADCs) and other targeted therapies.
• Chemical Biology Research: Employed as a tool compound for studying enzyme mechanisms and protein-protein interactions.
• Fine Chemical Production: Acts as a starting material or intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Boc-4-Amino-3-Hydroxybutanoic Acid
CAS No.	69489-07-2
Molecular Formula	C₉H₁₇NO₅
Molecular Weight	219.24 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3-hydroxybutanoic acid; (R/S)-4-[(tert-Butoxycarbonyl)amino]-3-hydroxybutyric acid; 3-Hydroxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid; Boc-AHBA; Boc-4-Amino-3-Hydroxybutyric Acid; N-Boc-4-amino-3-hydroxybutanoic acid; N-(tert-Butoxycarbonyl)-4-amino-3-hydroxybutanoic acid
EINECS	Contact for details

Quality Control

Our Boc-4-Amino-3-Hydroxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.