Description

1,2-o-Dihexadecyl-Rac-Glycero-3-Phosphocholine CAS NO 69483-37-0 is a high-purity, synthetic phospholipid widely recognized as a key component in the formulation of liposomes and lipid nanoparticles. This compound is critical for creating stable, uniform lipid bilayers, making it indispensable for advanced drug delivery systems and membrane research. It is primarily utilized by pharmaceutical R&D teams, formulation scientists, and academic researchers working on next-generation therapeutics and biomimetic studies.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: Serves as a primary structural phospholipid for creating stable vesicles for drug encapsulation, including mRNA vaccines and chemotherapeutic agents.
• Drug Delivery Systems: Used to enhance the bioavailability, targeting, and controlled release of active pharmaceutical ingredients (APIs).
• Biomembrane & Model Membrane Studies: Essential for constructing artificial cell membranes to study permeability, protein-lipid interactions, and membrane dynamics.
• Biophysical Research: Employed in techniques like calorimetry, spectroscopy, and microscopy to investigate lipid bilayer properties and phase behavior.
• Cosmetic & Dermal Formulations: Acts as an advanced emollient and penetration enhancer in high-end skincare products.
• Diagnostic Reagents: Used in the development of diagnostic assays and kits that require stable lipid interfaces.

Basic Information

Product Name	1,2-o-Dihexadecyl-Rac-Glycero-3-Phosphocholine
CAS No.	69483-37-0
Molecular Formula	C42H86NO8P
Molecular Weight	764.10 g/mol
Synonyms	1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine; DHPC; Dipalmitoyl Phosphatidylcholine Analog; rac-1,2-Dihexadecyl-sn-glycero-3-phosphocholine; 1,2-Dihexadecylphosphatidylcholine; DPPC Ether Lipid; Phosphatidylcholine, 1,2-di-O-hexadecyl-rac-glycero-3-; Lipoid PC-16:0/16:0 (Ether)
EINECS	Contact for details

Quality Control

Our 1,2-o-Dihexadecyl-Rac-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.