Description

Progesterone 11-Hemisuccinate-(2-Iodohistamine) is a chemically modified derivative of progesterone, designed for advanced research and development applications. This compound is valued for its utility as a key intermediate in the synthesis of novel steroid conjugates and labeled probes for diagnostic and investigative purposes. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on endocrinology, radiopharmaceuticals, and molecular imaging.

Application

• Pharmaceutical Research: Serves as a critical intermediate in the development of novel steroid-based therapeutics and diagnostic agents.
• Radiopharmaceutical Synthesis: Used in the preparation of iodine-labeled progesterone analogs for molecular imaging and targeted therapy research.
• Bioconjugation & Probe Development: Acts as a building block for creating hormone-protein conjugates for immunoassays and antibody development.
• Endocrinology Studies: Employed in biochemical research to study progesterone receptor interactions and signaling pathways.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.
• Specialty Chemical Manufacturing: A key precursor for custom synthesis projects requiring modified steroid structures.

Basic Information

Product Name	Progesterone 11-Hemisuccinate-(2-Iodohistamine)
CAS No.	69436-84-6
Molecular Formula	C31H42IN3O5
Molecular Weight	687.50 g/mol
Synonyms	11β-Hemisuccinyloxyprogesterone 2-Iodohistamine Amide; Progesterone 11-Hemisuccinate 2-Iodohistamine Conjugate; 11β-(Carboxypropionyloxy)pregn-4-ene-3,20-dione 2-Iodohistamine Amide; P4-11-HS-2-I-His; 2-Iodo-N-(2-(1H-imidazol-4-yl)ethyl)-4-(((8R,9S,10R,13S,14S,17S)-3-oxo-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)oxy)-4-oxobutanamide
EINECS	Contact for details

Quality Control

Our Progesterone 11-Hemisuccinate-(2-Iodohistamine) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.