Description

2,6-Difluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the fluorine substituents, enabling the construction of complex molecules with tailored characteristics. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro motif can enhance biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Polymer and Material Science: Incorporated into monomers for the synthesis of high-performance polymers, such as polyamides and polyimides, with improved thermal and chemical resistance.
• Liquid Crystal and OLED Materials: Acts as a building block for fluorinated components in electronic display and lighting materials.
• Custom Synthesis and R&D: A valuable reagent for medicinal chemistry and process research in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	2,6-Difluorobenzylamine
CAS No.	69385-30-4
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	(2,6-Difluorophenyl)methanamine; 2,6-Difluorobenzyl amine; 1-(2,6-Difluorophenyl)methanamine; Benzenemethanamine, 2,6-difluoro-; 2,6-Difluoro-α-toluidine; 2,6-DFBA; α-Amino-2,6-difluorotoluene
EINECS	Contact for details

Quality Control

Our 2,6-Difluorobenzylamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.