Description

5-Hexyne-1,4-Diamine is a specialized alkyne-containing diamine building block of significant interest in advanced organic synthesis. Its unique bifunctional structure, featuring both a terminal alkyne and two primary amine groups, makes it a versatile precursor for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to develop novel polymers, ligands, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring alkyne-amine click chemistry for bioconjugation or library development.
• Polymer & Resin Synthesis: Serves as a cross-linking agent or monomer in the production of specialty polyamides, polyurethanes, and epoxy resins with tailored thermal and mechanical properties.
• Ligand & Catalyst Development: Used to create chelating ligands for metal catalysts in asymmetric synthesis and other catalytic processes.
• Agrochemical Research: Employed in the design and synthesis of new crop protection agents and plant growth regulators.
• Surface Modification & Coatings: Facilitates the functionalization of surfaces and nanoparticles due to its reactive amine and alkyne groups.
• Chemical Biology & Bioconjugation: Enables site-specific labeling of biomolecules (proteins, nucleic acids) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.

Basic Information

Product Name	5-Hexyne-1,4-Diamine
CAS No.	69355-11-9
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	1,4-Diamino-2-hexyne; 2-Hexyne-1,4-diamine; 5-Hexyne-1,4-diyldiamine; 1,4-Diamino-5-hexyne; 2-Butyn-1,4-diamine (homolog); Alkyne-diamine C6
EINECS	Contact for details

Quality Control

Our 5-Hexyne-1,4-Diamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, assay, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.