Description

2-Methylbicyclo[2.2.2]octane-2-carboxamide is a specialized bicyclic organic compound featuring a rigid, cage-like structure with an amide functional group. This unique molecular architecture makes it a valuable intermediate in advanced organic synthesis and pharmaceutical research, particularly for developing novel active pharmaceutical ingredients (APIs) and complex fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for applications requiring high structural precision and stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) or requiring specific three-dimensional pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its bicyclic framework can contribute to unique biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor or core structure for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with enhanced thermal stability and rigidity due to its bulky, constrained geometry.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions where a rigid, hydrophobic probe is advantageous.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing complex musk-like odorants or flavor compounds with high stability.

Basic Information

Product Name	2-Methylbicyclo[2.2.2]octane-2-carboxamide
CAS No.	69352-99-4
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	2-Carbamoyl-2-methylbicyclo[2.2.2]octane; 2-Methylbicyclo[2.2.2]octane-2-carboxylic acid amide; 2-Methyl-2-bicyclo[2.2.2]octanecarboxamide; 2-Methyl-2-adamantanecarboxamide (common misnomer based on structure); 2-Methyl-2-norbornanecarboxamide (related structural name); Bicyclo[2.2.2]octane-2-carboxamide, 2-methyl-; 2-Methyltricyclo[2.2.2.0]octane-2-carboxamide
EINECS	Contact for details

Quality Control

Our 2-Methylbicyclo[2.2.2]octane-2-carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. For research and development purposes, we offer material in standard laboratory grades, with the capability to supply custom purities and specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.