Description

Phenacetin-D5 is a stable isotope-labeled analog of the analgesic and antipyretic compound Phenacetin, where five hydrogen atoms are replaced by deuterium. This high-purity internal standard is critical for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily utilized by analytical laboratories and research institutions in the pharmaceutical and forensic toxicology sectors for method development and validation.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of Phenacetin and related metabolites in biological matrices.
• Method Development and Validation in pharmaceutical research and bioanalytical studies.
• Metabolite Tracing and Pharmacokinetic Studies to understand drug absorption, distribution, metabolism, and excretion (ADME).
• Forensic and Clinical Toxicology analysis for accurate measurement of Phenacetin in complex samples.
• Quality Control and Assurance in reference material and certified standard production.
• Stable Isotope Dilution Assays (SIDA) to achieve high precision in quantitative analytical chemistry.

Basic Information

Product Name	Phenacetin-D5
CAS No.	69323-74-6
Molecular Formula	C10H8D5NO2
Molecular Weight	183.23 g/mol (approx.)
Synonyms	N-(4-Ethoxyphenyl)acetamide-d5; 4'-Ethoxyacetanilide-d5; Acetophenetidin-d5; p-Acetophenetidide-d5; p-Ethoxyacetanilide-d5; Deuterated Phenacetin; Phenacetin (phenyl-D5)
EINECS	Contact for details

Quality Control

Our Phenacetin-D5 is manufactured under controlled conditions to ensure exceptional isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and Mass Spectrometry, to confirm identity, chemical purity, and deuterium enrichment. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.