Description

n-Nitrosoethylmethyl-D3-Amine is a stable isotope-labeled analog of n-Nitrosoethylmethylamine, a nitrosamine compound of significant research interest. This deuterated version is an essential analytical standard for precise quantification and method development in modern laboratories. It is primarily utilized by researchers and quality control professionals in the pharmaceutical, environmental, and food safety sectors who require high-fidelity internal standards for trace analysis.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical deuterated internal standard for the accurate quantification of nitrosamine impurities via LC-MS/MS and GC-MS methods.
• Pharmaceutical Impurity Testing: Used in the development and validation of analytical methods to detect and quantify genotoxic nitrosamine impurities in active pharmaceutical ingredients (APIs) and drug products, supporting regulatory compliance (e.g., FDA, EMA).
• Metabolic and Toxicological Studies: Enables tracking and studying the metabolism, distribution, and toxicokinetics of n-Nitrosoethylmethylamine in biological systems.
• Environmental Analysis: Applied in the analysis of nitrosamine contaminants in water, soil, and air samples.
• Food and Beverage Safety: Supports testing for nitrosamine contamination in foodstuffs, such as cured meats and certain beverages.
• Method Development and Validation: Provides a stable, isotopically distinct reference point for improving the accuracy, precision, and reliability of analytical procedures.
• Quality Control and Assurance: Essential for laboratory QA/QC protocols to ensure the accuracy of nitrosamine testing in various matrices.

Basic Information

Item	Details
Product Name	n-Nitrosoethylmethyl-D3-Amine
CAS No.	69278-54-2
Molecular Formula	C3D3H3N2O
Molecular Weight	92.11 g/mol
Synonyms	N-Nitrosoethylmethyl-d3-amine; N-Nitroso-N-ethyl-N-methyl-d3-amine; N-Ethyl-N-methyl-d3-nitrosamine; N-Methyl-N-ethyl-d3-nitrosamine; NMEA-d3; N-Nitrosomethylethylamine-d3; Deuterated N-Nitrosoethylmethylamine; Ethylmethylnitrosamine-d3
EINECS	Contact for details

Quality Control

Every batch of n-Nitrosoethylmethyl-D3-Amine is manufactured and analyzed under strict quality management systems to ensure the highest standards of isotopic purity and chemical identity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA), detailing batch-specific purity, isotopic enrichment, and analytical results, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.