Description

3',4'-Dihydroxynomifensine is a key chemical intermediate and reference standard of significant interest in pharmaceutical research and development. Its primary value lies in its role as a metabolite and synthetic precursor in the study of catecholamine-related compounds. This product is essential for researchers and manufacturers in the pharmaceutical and life science sectors, particularly those focused on neurochemistry, drug metabolism studies, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug substance and metabolite analysis.
• Metabolite Research: Serves as a critical standard in pharmacokinetic and pharmacodynamic studies related to nomifensine and analogous structures.
• Chemical Synthesis Intermediate: Employed as a building block in the research-scale synthesis of novel catecholamine derivatives and complex organic molecules.
• Biochemical Research: Utilized in enzymatic and receptor-binding assays to study catechol-O-methyltransferase (COMT) and related pathways.
• Academic & Institutional Research: A vital reagent for universities and R&D institutions conducting fundamental research in medicinal chemistry and neuropharmacology.

Basic Information

Product Name	3',4'-Dihydroxynomifensine
CAS No.	69275-19-0
Molecular Formula	C16H18N2O2
Molecular Weight	270.33 g/mol
Synonyms	4-(3,4-Dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-8-amine; 8-Amino-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline; Nomifensine Dihydroxy Metabolite; 3',4'-DHN; 1,2,3,4-Tetrahydro-8-amino-4-(3,4-dihydroxyphenyl)isoquinoline
EINECS	Contact for details

Quality Control

Our 3',4'-Dihydroxynomifensine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage of bulk quantities and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.