Description

Tris(3,5-Dimethylphenyl)Phosphine is a sterically hindered tertiary phosphine ligand, prized for its role in facilitating challenging catalytic transformations. Its value lies in enhancing reaction selectivity and catalyst stability in sophisticated organometallic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance ligands for cross-coupling and hydrogenation reactions.

Application

• As a ligand in transition metal catalysis, particularly for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Utilized in asymmetric hydrogenation and other stereoselective synthesis processes for chiral molecule production.
• Employed in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs) where robust catalytic systems are required.
• Acts as a stabilizing agent for reactive organometallic complexes and catalysts.
• Used in material science research for the development of novel polymers and functional materials.
• Applied in fine chemical synthesis for the production of specialty and high-value compounds.

Basic Information

Product Name	Tris(3,5-Dimethylphenyl)Phosphine
CAS No.	69227-47-0
Molecular Formula	C24H27P
Molecular Weight	346.44 g/mol
Synonyms	Tris(3,5-xylyl)phosphine; Tri(3,5-dimethylphenyl)phosphine; Phosphorous tris(3,5-dimethylphenyl); 3,5-Dimethylphenylphosphine; P(3,5-Me2C6H3)3; Ligand SPhos (Note: SPhos is a closely related but distinct ligand; included for search relevance).
EINECS	Contact for details

Quality Control

Our Tris(3,5-Dimethylphenyl)Phosphine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.