Description

Deoxycorticosterone Nitroxide is a specialized nitroxide derivative of the steroid hormone deoxycorticosterone, serving as a stable free radical. This compound is primarily valued as a spin label and probe in electron paramagnetic resonance (EPR) spectroscopy for studying molecular dynamics and structure in complex biological and chemical systems. It is essential for researchers and manufacturers in pharmaceutical R&D, biochemistry, and material science who require precise tools for investigating membrane fluidity, protein conformation, and polymer properties.

Application

• EPR/Spin Labeling Studies: As a stable nitroxide radical for probing local environment, mobility, and distances in biomolecules and synthetic polymers.
• Membrane Biophysics Research: Investigating lipid bilayer properties, membrane protein interactions, and fluidity in model and cellular membranes.
• Protein Dynamics Analysis: Site-directed spin labeling (SDSL) to study protein folding, conformational changes, and oligomerization.
• Polymer Science: Characterizing molecular motion, phase transitions, and microstructure in advanced polymeric materials.
• Antioxidant Mechanism Studies: Serving as a model compound or reference standard in research on radical scavenging and oxidative stress.
• Pharmaceutical Development: Potential use in the synthesis and study of novel steroid-based therapeutic agents or diagnostic tools.

Basic Information

Product Name	Deoxycorticosterone Nitroxide
CAS No.	69081-49-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	21-Hydroxypregn-4-ene-3,20-dione Nitroxide; 11-Deoxycorticosterone Nitroxyl; DOC Nitroxide; Steroid Nitroxide Spin Label; Pregn-4-ene-3,20-dione, 21-hydroxy-, nitroxide; Nitroxide derivative of Deoxycorticosterone; 21-Hydroxy-4-pregnene-3,20-dione nitroxide
EINECS	Contact for details

Quality Control

Our Deoxycorticosterone Nitroxide is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Product purity and radical stability are verified through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and specific tests is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability of the nitroxide radical. Keep the container in a dry, cool, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Purity (EPR)	Predominantly nitroxide radical
Solubility	Soluble in common organic solvents (e.g., chloroform, ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.