Description

3-(Trifluoromethyl)Crotonic Acid is a high-value fluorinated organic acid building block characterized by its reactive α,β-unsaturated carbonyl and trifluoromethyl groups. This unique structure makes it a critical intermediate for synthesizing advanced molecules with enhanced biological activity and chemical stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorinated moiety can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or modifier in the production of specialty polymers and coatings with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A versatile reagent for academic and industrial research exploring new fluorination methodologies and the properties of fluoroorganic compounds.

Basic Information

Product Name	3-(Trifluoromethyl)Crotonic Acid
CAS No.	69056-67-3
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	(E)-4,4,4-Trifluoro-2-butenoic Acid; (E)-4,4,4-Trifluorocrotonic Acid; trans-3-(Trifluoromethyl)crotonic Acid; 3-(Trifluoromethyl)but-2-enoic Acid; 4,4,4-Trifluorocrotonic Acid; 2-Butenoic acid, 4,4,4-trifluoro-; TFMCA
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Crotonic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, store separately from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.