Description

5-(3-Carboxy-3-Hydroxypropyl)Nicotinamide Adenine Dinucleotide is a specialized, high-purity biochemical cofactor essential for advanced enzymatic research and bioprocess development. This compound matters as a critical reagent for studying and manipulating NAD(P)H-dependent enzyme systems, enabling breakthroughs in metabolic engineering and pharmaceutical synthesis. It is primarily needed by research institutions, diagnostic manufacturers, and biotechnology companies focused on developing novel biocatalysts, biosensors, and therapeutic agents.

Application

• Enzymology Research: Serves as a coenzyme or substrate in kinetic studies and mechanistic investigations of dehydrogenases, reductases, and other NAD(P)H-dependent enzymes.
• Diagnostic Kit Manufacturing: Used as a key component in the formulation of clinical diagnostic reagents and test strips for measuring metabolites like glucose, lactate, or cholesterol.
• Biocatalyst Development: Essential for screening and engineering novel enzymes used in the synthesis of chiral intermediates for pharmaceuticals and fine chemicals.
• Metabolic Pathway Analysis: Employed in vitro to study cellular metabolic fluxes, redox states, and the function of specific pathways in cell-free systems.
• Pharmaceutical R&D: Utilized in drug discovery programs targeting metabolic diseases, cancer, and aging, where NAD+ metabolism is a key focus area.
• Biosensor Construction: Integrated into electrochemical or optical biosensor platforms for the sensitive and selective detection of specific analytes.

Basic Information

Product Name	5-(3-Carboxy-3-Hydroxypropyl)Nicotinamide Adenine Dinucleotide
CAS No.	68889-85-0
Molecular Formula	C24H33N7O16P2
Molecular Weight	785.51 g/mol
Synonyms	3-Carboxy-3-hydroxypropyl-NAD; 3-CHP-NAD; 5-(3-Carboxy-3-hydroxypropyl)-NAD; NAD-3-CHP; 3-Carboxy-3-hydroxypropylnicotinamide adenine dinucleotide; Dinicotinyl-3-carboxy-3-hydroxypropyladenine; 5-(3-Carboxy-3-hydroxypropyl)-1,4-dihydronicotinamide adenine dinucleotide (oxidized form)
EINECS	Contact for details

Quality Control

Our 5-(3-Carboxy-3-Hydroxypropyl)Nicotinamide Adenine Dinucleotide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and in-vitro diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store desiccated under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Enzymatic)	≥ 90.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.