Description

2-Fluoro-4-Hydroxyphenylacetic Acid is a fluorinated aromatic acid derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both a carboxylic acid and a phenolic hydroxyl group adjacent to a fluorine atom, makes it a critical building block for constructing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies and for the development of diagnostic agents and molecular tags.
• Fine Chemical Synthesis: A versatile starting material for custom synthesis and the production of specialty chemicals, including dyes, pigments, and complex ligands for catalysis.

Basic Information

Product Name	2-Fluoro-4-Hydroxyphenylacetic Acid
CAS No.	68886-07-7
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-Fluoro-4-hydroxyphenylacetic acid; (2-Fluoro-4-hydroxyphenyl)acetic acid; 4-Hydroxy-2-fluorophenylacetic acid; 2-Fluoro-4-hydroxybenzeneacetic acid; FAHPA; 68886-07-7; p-Hydroxy-o-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Each batch of 2-Fluoro-4-Hydroxyphenylacetic Acid is analyzed using advanced techniques like HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, meeting the exacting requirements of pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and acid chlorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.