Description

tert-Butyl 2-(4-Fluorophenyl)Acetate is a high-purity organic building block and ester derivative, serving as a critical intermediate in advanced chemical synthesis. Its value lies in the strategic combination of the acid-labile tert-butyl ester protecting group and the versatile 4-fluorophenyl moiety, enabling precise molecular construction. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated compounds' enhanced bioactivity and stability.
• Organic Synthesis Reagent: Serves as a protected carboxylic acid precursor in multi-step synthetic routes, including peptide coupling and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced organic materials where fluorinated aromatic units are required.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	tert-Butyl 2-(4-Fluorophenyl)Acetate
CAS No.	68825-45-6
Molecular Formula	C₁₂H₁₅FO₂
Molecular Weight	210.24 g/mol
Synonyms	2-(4-Fluorophenyl)acetic acid tert-butyl ester; tert-Butyl (4-fluorophenyl)acetate; 4-Fluorophenylacetic acid tert-butyl ester; (4-Fluorophenyl)acetic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 2-(4-fluorophenyl)acetate; t-Butyl 4-fluorophenylacetate; tert-Butyl 4-fluorobenzeneacetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4-Fluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.