Description

Rac-Apomorphine-13C-D3 Hcl is a stable isotope-labeled analog of apomorphine, a potent dopamine receptor agonist. This compound is specifically designed for use as an internal standard in quantitative bioanalytical methods, providing unmatched accuracy and reliability for pharmacokinetic and metabolic studies. It is an essential tool for pharmaceutical researchers, contract research organizations (CROs), and analytical laboratories engaged in drug development and forensic analysis, particularly for neurological and psychiatric disorders.

Application

• Bioanalytical Internal Standard: Primary use as a high-purity reference standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) quantification of apomorphine and its metabolites in biological matrices.
• Pharmacokinetic Research: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical studies.
• Metabolite Identification: Facilitates the structural elucidation and quantification of drug metabolites using advanced mass spectrometry techniques.
• Method Development & Validation: Critical for developing, optimizing, and validating robust, GLP-compliant analytical methods in regulatory submissions.
• Forensic Toxicology: Used in confirmatory testing and accurate quantification of apomorphine in forensic and anti-doping control laboratories.
• Quality Control (QC) Testing: Serves as a certified reference material for in-house quality control of pharmaceutical products containing apomorphine.

Basic Information

Product Name	Rac-Apomorphine-13C-D3 Hcl
CAS No.	68821-04-5
Molecular Formula	C17H1413C1D3NO2•HCl
Molecular Weight	~312.8 g/mol (for labeled form)
Synonyms	6aβ-Aporphine-10,11-diol, 5,6,6a,7-tetrahydro- (labeled); (Rac)-Apomorphine-13C-D3 Hydrochloride; 13C-D3-Apomorphine HCl; Deuterated and 13C-labeled Apomorphine HCl; Apomorphine-d3-13C hydrochloride; 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol-13C-D3 hydrochloride; RAC-APOMORPHINE-13C-D3 HYDROCHLORIDE
EINECS	Contact for details

Quality Control

Every batch of Rac-Apomorphine-13C-D3 Hcl is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation via advanced spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for use in GLP and ISO 17025 accredited laboratories, supporting reliable and reproducible scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥99 atom % 13C; ≥98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.