Description

[6R-(6Alpha,7Beta)]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate in the cephalosporin antibiotic class. This compound is critical for the synthesis of potent third-generation cephalosporins, offering a high-purity building block for complex pharmaceutical manufacturing. It is primarily required by research institutions and pharmaceutical companies engaged in the development and production of advanced β-lactam antibiotics.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A crucial intermediate in the chemical synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and creation of new antibiotic analogs with improved efficacy.
• Process Chemistry: Serves as a high-value starting material or intermediate in scale-up and optimization studies for antibiotic production.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of cephalosporin drugs.
• Antibacterial Agent Development: Fundamental component in research targeting new antibacterial agents to combat resistant bacterial strains.

Basic Information

Product Name	[6R-(6Alpha,7Beta)]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	68779-03-3
Molecular Formula	C₂₂H₂₁N₇O₆S₂
Molecular Weight	543.57 g/mol
Synonyms	7-[(Formyloxy)phenylacetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefoperazone Formyl Ester; Cefoperazone Formate Ester; Cefoperazone Formyloxy Ester; (6R,7R)-7-[(R)-2-(Formyloxy)-2-phenylacetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefoperazone Precursor; Cefobid Intermediate
EINECS	Contact for details

Quality Control

Our [6R-(6Alpha,7Beta)]-7-[(Formyloxy)Phenylacetamido]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.