Description

6-Trifluoromethyl-Indan-1-Ylamine Hcl is a high-purity, fluorinated amine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the indane scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the metabolic stability imparted by the fluorine atoms.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorination on chemical reactivity and biological activity.
• Fine Chemical Production: Used in multi-step syntheses to introduce the 1-aminoindane core with a trifluoromethyl substituent into complex molecular architectures.

Basic Information

Product Name	6-Trifluoromethyl-Indan-1-Ylamine Hcl
CAS No.	68755-41-9
Molecular Formula	C11H11ClF3N
Molecular Weight	249.66 g/mol
Synonyms	1-Amino-6-(trifluoromethyl)indane hydrochloride; 6-(Trifluoromethyl)-1-indanamine hydrochloride; 6-Trifluoromethyl-1-indanamine HCl; (6-Trifluoromethyl-2,3-dihydro-1H-inden-1-yl)amine hydrochloride; 1-Indanamine, 6-(trifluoromethyl)-, hydrochloride; 6-Trifluoromethylindan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-Indan-1-Ylamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.