Description

1,2-Dimyristoylglycero-3-Phosphatidyl-N,n-Dimethylethanolamine is a synthetic, high-purity phospholipid derivative, specifically a dimethylphosphatidylethanolamine (DMPE) with myristoyl (C14:0) fatty acid chains. This compound is a critical functional lipid used to modulate the surface properties and stability of lipid-based delivery systems. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise control over vesicle charge, membrane fusion characteristics, and formulation performance.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: As a structural and functional component to influence membrane charge, stability, and encapsulation efficiency for drug delivery.
• mRNA Vaccine & Therapeutic Delivery Systems: A key excipient in cationic or ionizable lipid formulations to enhance cellular uptake and endosomal escape.
• Biomimetic Membrane Research: Used in model membrane studies to investigate lipid-protein interactions, membrane fluidity, and fusion processes.
• Diagnostic Reagents: Incorporated into lipid bilayers for biosensors, assays, and diagnostic kits requiring stable, functionalized surfaces.
• Cosmetic Nanocarriers: Employed in advanced cosmetic formulations for the stable encapsulation and targeted delivery of active ingredients.
• Cell Culture & Transfection Reagents: A component in lipid mixtures used for in vitro transfection to introduce nucleic acids into cells.

Basic Information

Product Name	1,2-Dimyristoylglycero-3-Phosphatidyl-N,n-Dimethylethanolamine
CAS No.	68755-14-6
Molecular Formula	C35H70NO8P
Molecular Weight	663.90 g/mol
Synonyms	DMPE (C14:0); 1,2-Dimyristoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine; DMPE-Dimyristoyl; Phosphatidyldimethylethanolamine (C14:0); DMPE Lipid; 1,2-Ditetradecanoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine; N,N-Dimethyl-1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine; DMPE (14:0/14:0)
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoylglycero-3-Phosphatidyl-N,n-Dimethylethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and life science research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and potentially oxidizable nature. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.