Description

5-Methyltetrahydrofolic Acid Barium is a stabilized, high-purity salt form of the biologically active folate coenzyme. This compound is critical for ensuring consistent bioavailability and stability in advanced nutritional and pharmaceutical formulations. It is primarily required by manufacturers in the nutraceutical, pharmaceutical, and clinical research sectors seeking a reliable source of metabolically active folate.

Application

• Pharmaceutical Intermediates: As a key active pharmaceutical ingredient (API) or precursor in the synthesis of prescription-grade folate supplements and medications.
• Premium Nutraceuticals: Formulation of high-efficacy dietary supplements, prenatal vitamins, and methylation support products targeting enhanced bioavailability.
• Clinical Research & Diagnostics: Use as a standard or reagent in biochemical research, metabolic studies, and diagnostic assay development.
• Food & Beverage Fortification: For the nutritional fortification of functional foods and medical foods requiring a stable, bioavailable folate source.
• Cell Culture Media: As a specialized component in serum-free and defined cell culture media for biopharmaceutical production and advanced cell biology.

Basic Information

Product Name	5-Methyltetrahydrofolic Acid Barium
CAS No.	68703-91-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(6S)-5-Methyl-5,6,7,8-tetrahydrofolic Acid Barium Salt; L-Methylfolate Barium; Metafolin® Barium Salt; 5-MTHF Barium; 5-Methyltetrahydrofolate Barium; Barium (6S)-5-methyl-5,6,7,8-tetrahydrofolate; Barium 5-MTHF; Quatrefolic® Barium Salt
EINECS	Contact for details

Quality Control

Our 5-Methyltetrahydrofolic Acid Barium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and microbiological data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. The product is hygroscopic (moisture-sensitive) and must be handled in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/UV)	Conforms
Assay (HPLC)	≥ 95.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Total Aerobic Microbial Count	≤ 1000 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.