Description

Mecasermin CAS NO 68562-41-4 is a recombinant human insulin-like growth factor-1 (rhIGF-1) analog, representing a critical therapeutic protein. This compound is essential for its role in stimulating cell growth and proliferation, making it a vital active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and research institutions focused on developing treatments for growth disorders, severe insulin resistance, and related metabolic conditions.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of injectable drugs to treat primary insulin-like growth factor-1 deficiency (IGFD).
• Research Biochemical for in vitro and in vivo studies of cell growth, metabolism, and signal transduction pathways.
• Therapeutic Development for conditions involving severe insulin resistance, such as type A insulin resistance syndrome and Rabson-Mendenhall syndrome.
• Metabolic Disorder Research to investigate the role of the IGF-1 axis in diabetes and aging.
• Reference Standard for quality control and analytical method development in biopharmaceutical laboratories.

Basic Information

Product Name	Mecasermin
CAS No.	68562-41-4
Molecular Formula	C331H527N97O101S7
Molecular Weight	~7649.0 g/mol
Synonyms	Recombinant Human Insulin-like Growth Factor I; rhIGF-1; IGF-I; Somatomedin C; Mecasermin [INN]; Mecasermin (rDNA origin); Insulin-like Growth Factor 1, Human Recombinant; CAS 68562-41-4
EINECS	Contact for details

Quality Control

Our Mecasermin is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting high-grade standards suitable for pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions at -20°C or below.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay (Bioactivity)	≥ 95.0% of labelled potency
Water Content (KF)	≤ 5.0%
Bacterial Endotoxins	< 1.0 EU/mg
Residual Host Cell DNA	< 10 pg/mg
Residual Host Cell Proteins	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.