Description

7-Acca Impurity A is a key chemical reference standard and process impurity encountered in the synthesis of advanced pharmaceutical intermediates. Its precise characterization is critical for ensuring the purity, safety, and regulatory compliance of final active pharmaceutical ingredients (APIs). This compound is primarily required by research institutions, analytical laboratories, and manufacturers engaged in the development and quality control of cephalosporin-class antibiotics and other fine chemicals.

Application

• Pharmaceutical Reference Standard: Used as a certified impurity standard for analytical method development, validation, and quality control testing in API manufacturing.
• Process Chemistry Research: Serves as a critical marker for monitoring and optimizing synthetic pathways, helping to minimize impurity formation during production.
• Regulatory Compliance & Documentation: Essential for preparing impurity profiles and regulatory submission dossiers for health authorities like the FDA and EMA.
• Analytical Laboratory Use: Employed in HPLC, LC-MS, and other chromatographic systems for calibration, identification, and quantification of related substances.
• Academic & Industrial R&D: Utilized in chemical research for studying reaction mechanisms and degradation pathways of complex organic molecules.

Basic Information

Product Name	7-Acca Impurity A
CAS No.	68506-27-4
Molecular Formula	C8H10N2O3S
Molecular Weight	214.24 g/mol
Synonyms	(6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-ACA Impurity A; 7-Aminocephalosporanic Acid Impurity A; 7-ACA Related Compound A; 3-Methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (common misassignment); 7-ADCA Impurity A (related context); 7-ACCA
EINECS	Contact for details

Quality Control

Every batch of 7-Acca Impurity A is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity confirmation, purity analysis, and impurity profiling using advanced techniques like HPLC and LC-MS to ensure they meet the exacting standards required for pharmaceutical analysis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Maximum Unknown Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.