Description

2-Methyl-4-Oxo-4-(4'-Fluorophenyl)Butyric Acid is a high-purity fluorinated organic acid intermediate of significant importance in advanced pharmaceutical synthesis. Its core value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability. This product is essential for research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel drugs, agrochemicals, and other specialty organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those containing a fluorophenyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluorine atom enhances biological activity and environmental persistence.
• Fine Chemical Production: Serves as a versatile precursor for creating other specialty fluorinated organic compounds used in material science and electronics.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and developing novel fluorinated molecules with potential therapeutic or material applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	2-Methyl-4-Oxo-4-(4'-Fluorophenyl)Butyric Acid
CAS No.	68415-18-9
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	4-(4-Fluorophenyl)-2-methyl-4-oxobutanoic acid; 4-(4-Fluorobenzoyl)-2-methylbutyric acid; 2-Methyl-4-(4-fluorobenzoyl)butanoic acid; 4-Fluoro-α-methyl-γ-oxobenzenebutanoic acid; γ-Oxo-4-fluorobenzene-α-methylbutyric acid; 4'-Fluoro-2-methyllevulinic acid; (4-Fluorophenyl)(3-carboxy-1-methylpropyl)ketone
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Oxo-4-(4'-Fluorophenyl)Butyric Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.