Description

Ceftizoxime Sodium is a semi-synthetic, broad-spectrum third-generation cephalosporin antibiotic. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains. This product is essential for pharmaceutical manufacturers and research institutions developing injectable antibiotic formulations for serious infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of sterile injectable antibiotic products.
• Hospital & Clinical Use: Treatment of severe infections such as lower respiratory tract infections, urinary tract infections, intra-abdominal infections, and septicemia.
• Research & Development: Used in microbiological studies, antibiotic resistance research, and the development of new combination therapies.
• Veterinary Medicine: Potential application in treating bacterial infections in animals under veterinary guidance.
• Reference Standard: Serves as a chemical reference standard in quality control laboratories for HPLC and other analytical methods.

Basic Information

Product Name	Ceftizoxime Sodium
CAS No.	68401-82-1
Molecular Formula	C13H12N5NaO5S2
Molecular Weight	405.38 g/mol
Synonyms	Ceftizoxime Sodium Salt; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; FK 749; SKF 88373; Ceftizox; Cefizox; Epocelin; Ceftizoximum Natricum
EINECS	Contact for details

Quality Control

Our Ceftizoxime Sodium is manufactured under strict quality systems. It undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and microbiological purity is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	6.0 - 8.0
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (if required)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.