Description

Pyridoxal Diphosphate (PLP) is the metabolically active coenzyme form of vitamin B6, serving as an essential cofactor for a vast array of enzymatic reactions. Its primary commercial value lies in its critical role in amino acid metabolism, including transamination, decarboxylation, and racemization, making it indispensable for research and production in life sciences. This high-purity biochemical is primarily targeted at the pharmaceutical, biotechnology, and advanced research sectors for applications in enzyme studies, diagnostic reagent formulation, and cell culture media supplementation.

Application

• Enzyme Cofactor in Biochemical Research: Essential for in vitro studies of aminotransferases, decarboxylases, and other PLP-dependent enzymes.
• Pharmaceutical Intermediates: Used in the synthesis and research of specialized pharmaceuticals and active metabolites.
• Diagnostic Reagents: A key component in clinical diagnostic kits for measuring specific enzyme activities (e.g., ALT, AST) in blood samples.
• Cell Culture & Fermentation: Added to defined cell culture media and fermentation broths to support optimal growth and protein expression.
• Nutritional & Cosmetic Science: Investigated for advanced applications in nutraceuticals and cosmeceuticals due to its fundamental metabolic role.
• Biocatalysis: Employed in industrial biocatalytic processes requiring PLP-dependent enzymes for chiral synthesis.

Basic Information

Product Name	Pyridoxal Diphosphate
CAS No.	68385-44-4
Molecular Formula	C8H10NO8P2
Molecular Weight	325.11 g/mol
Synonyms	PLP; Pyridoxal 5'-Diphosphate; Pyridoxal 5'-Phosphate; Codecarboxylase; Pyridoxal Phosphate; Vitamin B6 Phosphate; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-(Dihydrogen Phosphate); Coenzyme B6
EINECS	Contact for details

Quality Control

Our Pyridoxal Diphosphate is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We support compliance with relevant standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to reach room temperature before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (HPLC/UV)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	2.0 - 4.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.