Description

8-Chloro-Fad CAS NO 68385-36-4 is a specialized organic compound belonging to the class of halogenated nucleoside analogs. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in studies investigating enzyme mechanisms, DNA/RNA synthesis inhibition, and metabolic pathways.
• Antiviral Agent Development: Serves as a precursor for compounds targeting viral polymerases in diseases such as hepatitis and herpes.
• Oncology Research: Employed in the development of chemotherapeutic agents that interfere with cellular replication.
• Fine Chemical Synthesis: A versatile intermediate for creating more complex, functionalized nucleoside derivatives.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	8-Chloro-Fad
CAS No.	68385-36-4
Molecular Formula	C15H16ClN5O4
Molecular Weight	365.77 g/mol
Synonyms	8-Chloro-2'-deoxy-2'-fluoroadenosine; 8-Chloro-2'-fluoro-2'-deoxyadenosine; 8-Cl-F-ara-A; 8-Chloro-fludarabine intermediate; 8-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine; 8-Cl-2'-F-ara-A; 8-Chloro-2'-fluoro-arabinofuranosyladenine
EINECS	Contact for details

Quality Control

Our 8-Chloro-Fad is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.