Description

Tetrahydro-1H-Pyrrolizine-7A(5H)-Carbonitrile is a specialized heterocyclic nitrile compound that serves as a critical advanced intermediate in organic synthesis. Its unique pyrrolizine core structure makes it a valuable building block for constructing complex molecules with potential biological activity. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Building block for developing new pesticides, herbicides, or plant growth regulators with novel modes of action.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Academic & Contract Research: Essential material for medicinal chemistry programs and process development in academic and CRO (Contract Research Organization) laboratories.
• Ligand & Catalyst Development: Potential starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Tetrahydro-1H-Pyrrolizine-7A(5H)-Carbonitrile
CAS No.	68295-48-7
Molecular Formula	C8H10N2
Molecular Weight	134.18 g/mol
Synonyms	7a-Cyanohexahydro-1H-pyrrolizine; 1H-Pyrrolizine-7a(5H)-carbonitrile, tetrahydro-; Hexahydro-1H-pyrrolizine-7a-carbonitrile; Tetrahydro-1H-pyrrolizine-7a-carbonitrile; 7a-Cyanooctahydropyrrolizine; Pyrrolizine-7a-carbonitrile, hexahydro-
EINECS	Contact for details

Quality Control

Our Tetrahydro-1H-Pyrrolizine-7A(5H)-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliable consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.