Description

Boc-Arg(Mts)-Oh is a protected amino acid derivative, specifically the Nα-Boc and Nω-Mts protected form of L-arginine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of arginine while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the automated synthesis of complex peptide sequences.
• Pharmaceutical R&D: For the research and development of novel peptide-based drugs, including hormones, antimicrobial peptides, and enzyme inhibitors.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for antibody-drug conjugates (ADCs) or diagnostic probes.
• Combinatorial Chemistry: Serves as a building block in libraries for high-throughput screening to identify bioactive compounds.
• Biochemical Research: For studying protein-protein interactions, enzyme mechanisms, and signal transduction pathways using synthetic peptide substrates or inhibitors.
• Custom Peptide Service: A fundamental reagent for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Boc-Arg(Mts)-Oh
CAS No.	68262-71-5
Molecular Formula	C19H30N4O6S
Molecular Weight	442.53 g/mol
Synonyms	Nα-Boc-Nω-Mts-L-arginine; Boc-Arg(Mts)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid; tert-Butyl N-[(2S)-5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-carboxypentyl]carbamate; Fmoc-Arg(Boc)-OH (Note: This is a common related compound, often searched in error); Boc-L-arginine(Mts)-OH; Nα-tert-Butyloxycarbonyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
EINECS	Contact for details

Quality Control

Our Boc-Arg(Mts)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.