Description

Isosulfan Blue CAS NO 68238-36-8 is a vital diagnostic dye belonging to the triarylmethane class, specifically engineered for lymphatic mapping and sentinel lymph node identification. Its core value lies in its selective and rapid uptake by the lymphatic system, providing surgeons with clear visual guidance during critical oncological procedures. This product is essential for medical research institutions, pharmaceutical developers, and manufacturers of diagnostic imaging agents who require a high-purity, reliable compound for advanced surgical and diagnostic applications.

Application

• Sentinel Lymph Node Biopsy (SLNB): Primary use as a vital blue dye for the intraoperative identification of the first lymph node(s) draining a tumor site in cancers such as breast cancer and melanoma.
• Lymphatic Mapping: Visualization of lymphatic vessel architecture and flow patterns in surgical and pre-surgical diagnostic procedures.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of more complex diagnostic agents and specialized dyes.
• Medical Research: Used in preclinical and clinical research studies investigating lymphatic system function, cancer metastasis, and the efficacy of new surgical techniques.
• Diagnostic Reagent Formulation: Incorporated into specialized diagnostic kits and formulations for hospital and clinical laboratory use.
• Tracer Studies: Employed in experimental models to study fluid drainage and pathways within biological systems.

Basic Information

Product Name	Isosulfan Blue
CAS No.	68238-36-8
Molecular Formula	C₂₇H₃₁N₂NaO₆S₂
Molecular Weight	566.67 g/mol
Synonyms	Patent Blue V; Acid Blue 1; Sulphan Blue; Isosulfan Blue Injectable; C.I. 42045; Erioglaucine A; Food Blue 3; FD&C Blue No. 1 (related aluminum lake); Alphazurine FG; Aniline Blue (not to be confused with other types)
EINECS	Contact for details

Quality Control

Our Isosulfan Blue is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and UV-Vis spectroscopy, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) documenting compliance with in-house specifications are provided. We support development projects and can discuss alignment with relevant pharmacopeial standards (e.g., USP, EP) for specific applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture, which may affect stability.

Specification

Item	Specification
Appearance	Dark blue to blue-violet powder
Identification (IR)	Conforms to reference spectrum
Identification (UV-Vis)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.