Description

1-(1-Bromoethyl)-4-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block characterized by its bromoethyl and trifluoromethyl substituents. This compound is essential for synthetic chemists seeking to introduce both lipophilic fluorine and versatile alkyl halide functionalities into target molecules. It is primarily utilized in the research and development of advanced materials and active pharmaceutical ingredients (APIs) where its unique structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: The benzyl bromide moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Kumada couplings for carbon-carbon bond formation.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on reaction kinetics and molecular conformation in academic and industrial R&D.

Basic Information

Product Name	1-(1-Bromoethyl)-4-(Trifluoromethyl)Benzene
CAS No.	68120-42-3
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	1-(1-Bromoethyl)-4-(trifluoromethyl)benzene; α-Bromoethyl-4-trifluoromethylbenzene; (1-Bromoethyl)(4-trifluoromethylphenyl)methane; 4-Trifluoromethyl-α-bromoethylbenzene; 1-Bromo-1-(4-(trifluoromethyl)phenyl)ethane; p-(1-Bromoethyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 1-(1-Bromoethyl)-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.